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0.0.21 #34

Merged
merged 58 commits into from
Nov 16, 2020
Merged

0.0.21 #34

merged 58 commits into from
Nov 16, 2020

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zktuong
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@zktuong zktuong commented Nov 16, 2020

Fixed bug where contigs that were assigned with light chain V/D/J but with a heavy chain constant and vice versa were not picked up during filter_bcr
Fixed bug where rpy2 couldn't read/convert data frame

Fixed and updated database versions.

Rehauled preprocessing steps for reannoate_genes; now both airr and changeo formats are created in tmp folder and the two dataframes are merged prior to reassign_isotype.

Removed the automatic population of .uns slot in anndata during transfer.

New pl.clone_overlap function to visualise clone overlap between samples as a circos plot.

modification to trim non-identical edges from the linking step. So now, it should be less like a ball of yarn unless there really is only identical sequences
Updated the preprocessing format to be consistent with AssignGenes.py and MakeDb.py behaviour from changeo
minor QoL change
wow found a bug that i didn't think of
Fixed bug where format_fasta wasn't properly trimming the trailing hypen number.

Overhauled the reannotation functions to now produce both blast and airr format outputs.

Commented out the code that was handling insertion of gaps in airr output.

The amino acid sequence alignments from airr output will be lifted onto the blast output file as a final step.
@zktuong zktuong merged commit 02ecd46 into master Nov 16, 2020
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