Waddington’s epigenetic landscape is probably the most famous and most powerful metaphor in developmental biology. Cells, represented by balls, roll downhill through a landscape of bifurcating valleys. Each new valley represents a possible cell fate and the ridges between the valleys maintain the cell fate once it has been chosen. (Quoted from reference)
Plot Waddington Epigenetic Landscape using ggridges, inspired by Figure 1 in reference, which could be used to illustate lineage tree or developmental hierarchy.
remotes::install_github("zzwch/waddingtonplot")
waddingtonplot::waddingtonPlot()
add external images using
require('ggplot2')
require('EBImage') # install.packages('EBImage')
waddingtonplot::waddingtonPlot(c(1,2,4,8), do.return = T) +
annotation_custom(grob = grid::rasterGrob(image = EBImage::readImage(files = "img_20180217191752.jpg")),
450, 550, 77, 85)