T-cell Receptor/Immunoglobulin Profiler (TRIP)
tripr is a Bioconductor package, written in
shiny that provides analytics services on
antigen receptor (B cell receptor immunoglobulin, BcR IG | T cell
receptor, TR) gene sequence data. Every step of the analysis can be
performed interactively, thus not requiring any programming skills. It
takes as input the output files of the IMGT/HighV-Quest
tool. Users can select to
analyze the data from each of the input samples separately, or the
combined data files from all samples and visualize the results
accordingly.
Functions for an R command-line use are also available.
tripr is distributed as a Bioconductor
package and requires R (version "4.2"), which can be installed on any
operating system from CRAN, and
Bioconductor (version "3.15").
To install tripr package enter the following commands in your R session:
if (!requireNamespace("BiocManager", quietly = TRUE)) {
install.packages("BiocManager")
}
BiocManager::install("tripr")
## Check that you have a valid Bioconductor installation
BiocManager::valid()Once tripr is successfully installed, it can be loaded as follow:
library(tripr)To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("tripr")