viperData

VIPER stands for the project titled, "Validation of Imaging Premarket Evaluationand Regulation."

The viperData repository and R package contain supplementary materials (data, R functions, R markdown files) for the following paper:

• Citation Brandon D. Gallas, Weijie Chen, Elodia Cole, Robert Ochs, Nicholas Petrick, Etta D. Pisano, Berkman Sahiner, Frank W. Samuelson, Kyle J. Myers, "Impact of prevalence and case distribution in lab-based diagnostic imaging studies," J. Med. Imag. 6(1), 015501 (2019), doi: 10.1117/1.JMI.6.1.015501.

Please cite this paper in any work that uses these materials.

All statistical analyses make use of the iMRMC package (Java GUI, R package).

Main Assets

• viperData_1.0.2.tar.gz: This is an R package (source) with the data and functions. Everything in this repository is in this package. See below for more details.

• viperData_1.0.2.zip: This is an R package (binary) with the data and functions. Everything in this repository is in this package. See below for more details.

• viperObs.csv: Individual observations of each reader reading each case. This data is also included as an R object (data frame) in the R package (Documentation).

• viperReaderQualifications.csv: Information from the VIPER reader recruitment qualification forms. This data is also included as an R object (data frame) in the R package (Documentation).

• dmistData.csv: Performance data manually translated from Pisano2005_NEJM_v353p1773 and its supplement. This data is also included as an R object (data frame) in the R package (Documentation)

Additional Assets

• An R-markdown file of the original manuscript (pdf version)
• An R-markdown file of a "Supplementary Materials" document (pdf version)
• The VIPER electronic case report form
• The VIPER instructions for ROC scores

Additional Data Objects in the R Package

• viperSummary
  • Summary performance statistics of the VIPER observations (Documentation).
• dmistRSsummary
  • Performance summaries from DMIST reader studies (Documentation)