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Unveiling the impact of bacteriophages targeting Shiga toxin-encoding Escherichia coli on the colon microbiome in vitro fermentation

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Phage-gut

An in vitro fermentation model to study the impact of bacteriophages targeting Shiga toxin-encoding Escherichia coli on the colonic microbiota npj Biofilms and Microbiomes (2022) https://doi.org/10.1038/s41522-022-00334-

Graça Pinto1,2,3, Sudarshan Shetty2$, Erwin G. Zoetendal2, Raquel F.S. Gonçalves1, Ana C. Pinheiro1, Carina Almeida1,3,4, Joana Azeredo1*, Hauke Smidt2*

1 CEB - Centre of Biological Engineering, University of Minho, 4710-057, Braga, Portugal. 2 Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands. 3 INIAV, IP-National Institute for Agrarian and Veterinary Research, Rua dos Lagidos, Lugar da Madalena, Vairão, Vila do Conde, Portugal 4 LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal

*Corresponding authors: Centre of Biological Engineering, Campus de Gualtar, 4710-057 Braga, Portugal. Tel: (+351) 253 604 424; e-mail: jazeredo@deb.uminho.pt Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE, Wageningen, The Netherlands; e-mail: hauke.smidt@wur.nl

$Present Address: Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen (UMCG), Groningen, The Netherlands

For queries about codes and analysis: Graça Pinto gracapinto[at]ceb[dot]uminho[dot]com

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