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Releases: HKU-BAL/Clair3

v1.0.10

28 Jul 15:04
a58ee60
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  1. Fixed an out of range bug when outputing GVCF for non-human genome (#317.
  2. Improve the calling speed when working with targeted amplicon data, Use —chunk_num=-1 to call variant without splitting genome into chunks (#306, contributor Elliot Hallmark).
  3. Updated LongPhase to version 1.7.3 (#321.

v1.0.9

15 May 10:14
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  1. Fixed an issue in VCF header(#305 by @Monica Palafox Roberts).
  2. Updated DP FORMAT description in the header.

v1.0.8

30 Apr 04:31
750f533
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  1. Fixed an issue in VCF output that caused occasional quality score small differences compared to GVCF output.
  2. Updated LongPhase to version 1.7.

v1.0.7

30 Apr 03:58
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  1. Added memory guards and test functions to the full-alignment calling C implementation (#286 by @Chris Wright).
  2. Increased the maximum mpileup read coverage to 2^20 to accomodate excessively high-coverage amplicon data (#292 by @Devon Ryan).
  3. Updated LongPhase to version 1.6.

v1.0.6

15 Mar 16:30
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  1. Fixed stack overflow issue when the read coverage is excessively high (#282 by @Chris Wright, #265 by @ymcki).
  2. Added reference caching for CRAM input (#278 by @Alex Leonard, #180 by @bartcharbon and @SamStudio8).
  3. Fixed a bug that outputs RefCall calls when no variant is called by full-alignment model (#271).
  4. Fixed a bug that variants below min coverage were still being called (#262).
  5. Set --min_snp_af and --min_indel_af to 0.0 when --vcf_fn is provided (#261).

v1.0.5

21 Dec 04:20
8f569c2
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  1. Fixed the issue showing wrong multi-allelic AF when read coverage is excessively high (#241).
  2. Added --base_err and --gq_bin_size options that can resolve the problem of having excessive GT ./. in GVCF output (#220).
  3. Modified logs (#231, #225)

v1.0.4

16 Jul 13:31
bfa87b5
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  1. Added showing command line and reference source in output VCF header.
  2. Fixed a bug in showing the AF tag for 1/2 genotypes.
  3. Added AD tag output.

v1.0.3

20 Jun 09:39
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Fixed a bug when the contig name contains colons (#203)

v1.0.2

22 May 08:30
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  1. Added PacBio HiFi Revio model, check Pre-trained model for model usage.
  2. Fixed a bug that halts the pipeline when there exists too few variant candidates (#198).

v1.0.1

26 Apr 16:18
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  1. Bumped up "WhatsHap" version to 1.7, the whatshap haplotag step is ~15% faster. (#193).
  2. Fixed PL tag output error when ALT is N (#191, contributor @Dennis Hendriksen).