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Python-based client for downloading data made available through portals powered by the GDC-based portal system..

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portal_client

Python-based client for downloading data files hosted by the Institute for Genome Sciences (IGS). There are several portals running on the internet to support various research efforts. Notably, the Neuroscience Multi-omic Archive (NeMO, https://nemoarchive.org/) and the Human Microbiome Project Data Analysis and Coordination Center (hmpdacc.org) use the portal to enable data exploration and download. The client accepts a manifest file as an input. This file contains URLs to the files to be downloaded. Manifest files can be generated using the shopping cart functionality of the portal's query interface.

Usage

When properly installed, portal_client will be available for direct invocation from the command line. Running which portal_client should yield a result, and will show precisely where the script is installed. General usage is available by running --help, or -h.

portal_client --help

This will output all the options that portal_client supports as well as a brief explanation of what each option means and how it modifies the execution.

1. Basic invocation

The following command is the most basic way of invoking the client. Simply by specifying the path to a downloaded manifest file with the -m, or --manifest option.

portal_client --manifest /path/to/my/manifest.tsv

Since manifests can list multiple URLs for an entry (a file can be obtained from multiple sources), when using portal_client in this manner, it uses a default set of protocols to download the data in the manifest. These protocols are, in priority order: HTTP, FTP, and S3. HTTP uses the http protocol for downloads of URLS starting with http:// or https://, while FTP uses the File Transfer Protocol for ftp:// links, and S3 will fetch data from Amazon AWS Simple Storage Service (S3) buckets. If a download cannot be performed for a file with HTTP, and the file is available via S3 and FTP, by default, the client will next attempt an FTP transfer, followed finally by S3...

2. Basic invocation on Amazon AWS

In the special case of executing portal_client on an EC2 instance on Amazon AWS, it's faster and more economical to retrieve data from S3, since there are no egress charges applied to such transfer. Therefore, the portal_client is configured to automatically detect when it is invoked on Amazon infrastructure and move the S3 protocol to the highest priority ahead of HTTP and FTP. The endpoint priority when running on EC2 is therefore: S3, HTTP, FTP, as opposed to the normal priority of HTTP, FTP, S3.

3. Altering the target directory

By default, portal_client will download data to the same directory (the "working directory"), that the user invoked portal_client from. To alter the location of where the data should be deposited, one must use the --destination option:

portal_client --manifest /path/to/my/manifest.tsv \
  --destination /path/to/my/destination/directory

4. Overriding the default endpoint-priority

Sometimes, it may be advantageous to override the default endpoints, and their priorities, that the portal_client will consider when downloading data. This is accomplished with the --endpoint-priority option.

portal_client --manifest /path/to/my/manifest.tsv --endpoint-priority S3

In the above example, portal_client will NOT consider or attempt to download data from HTTP or FTP urls. It will only use s3:// urls. Any URLs that do NOT use the s3:// protocol will be skipped.

5. Downloads using Aspera

The portal_client includes support for downloading data via Aspera's proprietary 'fasp' protocol. This is a proprietary high-performance protocol that uses UDP packets. The ascp utility must be installed, and available, on the same system as the portal client, or an error will occur. Please check for the availablity of 'ascp' with which:

which ascp

One must also explicitly include 'FASP' in the endpoint priority listing. In addition, the portal_client will also require the user to specify a username with the --user option and will interactively prompt the user for their Aspera server credential. The password will NOT be echoed to the screen/terminal for security reasons. Example:

portal_client --manifest /path/to/my/manifest.tsv \
  --endpoint-priority FASP,HTTP \
  --user myusername

The above command will consider and download data from both fasp:// and http:// urls, with preference given to Aspera.

Failure to specify the --user option will result in an error message when 'FASP' is used.

6. Downloads from Google Cloud Platform (GCP)

The portal_client is able to retrieve data from Google Cloud Storage buckets. Files in a google bucket, are addressable with URLs that begin with gs://, so if a manifest includes such URLs, one must enable the GS endpoint.

When accessing data in this manner from Google, a "client secrets" file must first be generated. Documentation for how that is accomplished is available from Google (Link) and is beyond the scope of this guide, but it is used to authorize the portal_client to access data in a Google storage bucket. Specify the path to the client secrets file with the --google-client-secrets option. Additionally, the ID of a valid Google project must also be specified with the --google-project-id option. A full example is below:

portal_client --manifest /path/to/my/manifest.tsv \
  --endpoint-priority GS,HTTP \
  --google-client-secrets /path/to/my/client-secrets.json \
  --google-project-id my-google-project-id

7. Disabling checksum validation

The portal_client usually verifies downloads after they happen by performing and MD5 checksum on the downloaded data, and comparing it to the checksums listed in the manifest file. However, if there is a mismatch, portal_client will consider the download to be corrupted, or failed, and will exit out with an error message. For very manifests that describe extremely large datasets, the checksumming operation can be very time consuming. To disable the checksum validation, simply pass an extra --disable-validation Example:

portal_client --disable-validation --manifest /path/to/my/manifest.tsv

8. Debug mode

Users can see verbose additional information when executing portal_client by passing the --debug option. This will typically result in a large amount of output and can be used to trace where problems may be occuring.