This repo contains the code, data, and supplemental information for the manuscript:
Ferrall-Fairbanks MC, Ball M, Padron E, and Altrock PM. Leveraging single-cell RNA sequencing experiments to model intratumor heterogeneity. JCO Clinical Cancer Informatics. (2019) doi:10.1200/CCI.18.00074
Code is written in both R and Mathematica.
The first place to look is in the Pipelines directory, where you can run the main pipelines using RStudio.
Then you can reproduce each figure using the notebook in the FigureX directory. For example Figure2.
If you would like to improve this code or have any feedback please file an issue or pull request. You can contact me a meghan.ferrall-fairbanks@moffitt.org