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Improve particles dissolution model #600

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Yuri05 opened this issue Apr 6, 2018 · 2 comments
Closed

Improve particles dissolution model #600

Yuri05 opened this issue Apr 6, 2018 · 2 comments
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subsystem: modeling type: task

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@Yuri05
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Yuri05 commented Apr 6, 2018 •
edited

Improve particles dissolution model.

Previous implementation:

part_01

New implementation:

part_02
@Yuri05 Yuri05 self-assigned this Apr 6, 2018
@msevestre
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@Yuri05 IS there a description somewhere of that's improved and how? If yes, Can we put it here

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Yuri05 commented Apr 6, 2018

will come in the next days

Yuri05 added a commit that referenced this issue Apr 6, 2018
@Yuri05
Fixes #600 Improve particles dissolution model (#601)
6347ed9 
* Replaced PKSimDB.mdb with 7.3 version
Adjusted code and tests to be able to run with 7.3 mdb

* Removed obsolete code

* Created "Precipitation rate of the tablet" parameter under ParticlesDrugReleaseSEGMENT transports

* Insoluble drug moved to application level (step 1: with 0 rate)

* Fixed rate of "Precipitation rate of the tablet"-parameter

* Defined "Solid drug", "Particle radius" and "Number of particles fraction" per Lumen segment (as children of ParticlesDrugRelease*-Transports)

* ParticlesDrugRelease*/Release rate of the tablet AND ParticlesDrugRelease* Rates

* Moved Insolubledrug back under ParticleBin

* Precipitation processes implemented

* BinDissolvedEvent (Caecum only)

* BinDissolvedEvent (all segments)

* Obsolete model parts removed (old BinDissolved-Event)

* Number of particles fraction defined per application (instead of per ParticleBin)

* Changed default particles formulation parameters (monodisperse, NoOfbins for polydisperse)

* Added testfile for project conversion tests

* PArticles: StopEvent fixed

* Particle dissolution integration tests added
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