Supybot is a robust (it doesn't crash), user friendly (it's easy to configure) and programmer friendly (plugins are extremely easy to write) Python IRC bot. It aims to be an adequate replacement for most existing IRC bots. It includes a very flexible and powerful ACL system for controlling access to commands, as well as more than 50 builtin plugins providing around 400 actual commands.
Limnoria is the project which continues development of Supybot since 2010.
Limnoria supports CPython 2.6, 2.7, 3.2, 3.3, 3.4, 3.5, 3.6, nightly; and Pypy 2 and 3. It works best with CPython 3.4 and higher. Python 2.5 and older versions are not supported.
If this is your first install, there is an install guide. You will probably be pointed to it if you ask on IRC how to install Limnoria. TL;DR version:
sudo apt-get install python3 python3-pip pip3 install --user limnoria supybot-wizard
If you have any trouble, feel free to swing by #supybot and #limnoria on freenode or #supybot at OFTC (we have a Limnoria there relaying, so either network works) and ask questions. We'll be happy to help wherever we can. And by all means, if you find anything hard to understand or think you know of a better way to do something, please post it on the issue tracker so we can improve the bot!
In Other languages
Only in French at the moment, located at #supybot-fr on freenode.