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Update: workaround libcrypto library issue
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The root cause of this issue seems to be a older version of samtools getting installed. A workaround is to activate the respective conda environment you created, and update your samtools installation manually to version 1.9.
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skarunan committed Aug 24, 2020
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Expand Up @@ -35,6 +35,25 @@ Should be changed to: ::

export PATH=/Users/xxx/miniconda2/condabin:/Users/xxx/miniconda2/bin:/usr/local/bin:/usr/bin:/bin:/usr/sbin:/sbin:/opt/X11/bin:/Users/xxx/miniconda2/envs/rapid/bin

* Library not loaded (libcrypto) *
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^

This issue was encountered in the following scenario: ::

Conda version: 4.8.4
OSX version: 10.15.6 Beta (19G36e)
Error:
dyld: Library not loaded: @rpath/libcrypto.1.0.0.dylib
Referenced from: /Users/siva/opt/anaconda3/envs/rapid10/bin/samtools
Reason: image not found
Abort trap: 6
This seems to be an issue with MacOS, and conda usage after recent updates. For unknown reasons an older version of samtools is getting installed. A workaround is to activate the respective conda environment you created, and update your samtools installation manually to version 1.9. You can use the following command: ::
conda install samtools==1.9


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