removed statement from README recommending single-stranded Domains fo…

…r extensions on the end of a strand, since 5'/3' modifications are now the recommended way to do that
UC-Davis-molecular-computing · Nov 19, 2020 · 6c13377 · 6c13377
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Showing 1 changed file with 1 addition and 1 deletion.
diff --git a/README.md b/README.md
@@ -543,7 +543,7 @@ There are different edit modes available, shown on the right side of the screen.
     Each strand is composed of one or more *bound domains*, defined to be a portion of a strand that exists on a single helix. A 5'/3' end of a bound domain that is not the 5'/3' end of the whole strand is one of these. They are not normally visible, but when these select modes are enabled, they become visible on mouseover and can be selected and dragged. Deleting a 5'/3' end of a bound domain deletes the whole bound domain. Ends can be moved, but unlike strands and domains, they can only be moved back and forth along their current helix.
 
   - **crossover, loopout:**
-    Two consecutive bound domains on a strand can be joined by either a *crossover*, which consists of no DNA bases, or a *loopout*, which is a single-stranded portion of the strand with one or more DNA bases. (Technically bound domains do not have to be bound to another strand, but the idea is that generally in a finished design, most of the bound domains will actually be bound to another. However, currently it is [unsupported](https://github.com/UC-Davis-molecular-computing/scadnano/issues/34) for a strand to begin or end with a loopout, so single-stranded bound domains are currently necessary to support single-stranded extensions on the end of a strand.)
+    Two consecutive bound domains on a strand can be joined by either a *crossover*, which consists of no DNA bases, or a *loopout*, which is a single-stranded portion of the strand with one or more DNA bases. (Technically bound domains do not have to be bound to another strand, but the idea is that generally in a finished design, most of the bound domains will actually be bound to another.)
 
     If many crossovers/loopouts are selected, all the crossovers can be converted to loopouts (or vice versa) by right-clicking on one fo them and picking "convert to loopout" (or "change loopout length" if a loopout; changing to length 0 converts it to a crossover).