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QUAST 5.0.0
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@alexeigurevich alexeigurevich released this 06 Aug 10:15
quast_5.0.0
e78e95e

QUAST 5.0.0 includes many features and fixed bugs, see the full list of changes here.

The most notable new feature is QUAST-LG mode (LG stands for "large genomes"). Now the tool can evaluate large-scale genome assemblies in a reasonable time (e.g., human assemblies in just a few hours). Significant speedup was achieved by both use of new fast aligner (minimap2) and the refactoring of alignment analyzing modules. We also introduced several new metrics suitable for large genomes but applicable to smaller organisms as well (e.g., k-mer-based completeness and correctness; the number of BUSCO genes; etc). The last but not the least, we developed the concept of upper bound assembly for a given genome and set of reads (theoretical limits on the assembly completeness and contiguity).

See http://cab.spbu.ru/software/quast-lg/ and our ISMB 2018 proceeding paper for more details on QUAST-LG and examples of its application to real datasets.

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