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Lead-DBS is a MATLAB toolbox facilitating deep brain stimulation electrode localization and connectomic neuroimaging.

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netstim/leaddbs

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LEAD-DBS

LEAD-DBS is NOT intended for clinical use!

About Lead-DBS

LEAD-DBS is a MATLAB toolbox facilitating the:

  • reconstruction of deep-brain-stimulation (DBS) electrodes in the human brain on basis of postoperative MRI and/or CT imaging
  • the visualization of localization results in 2D/3D
  • a group-analysis of DBS-electrode placement results and their effects on clinical results
  • simulation of DBS stimulations (calculation of volume of activated tissue – VAT)
  • diffusion tensor imaging (DTI) based connectivity estimates and fiber-tracking from the VAT to other brain regions (connectomic surgery)

Installation

Prerequisites

  • Recommended RAM size: 32GB or more
  • MATLAB version: R2022b or later
  • The following MATLAB toolboxes
    • MATLAB Image Processing Toolbox
    • MATLAB Signal Processing Toolbox
    • MATLAB Statistics and Machine Learning Toolbox
    • MATLAB Curve Fitting Toolbox (optional)
    • MATLAB Parallel Computing Toolbox (optional)
  • The SPM12 toolbox

Normal installation

Lead-DBS can be downloaded from our website in fully functional form.

Development installation

Alternatively, especially in case you wish to modify and contribute to Lead-DBS, you can

  • Make sure to meet the prerequisites
  • Clone the Lead-DBS repository from github.
  • Download the necessary data and unzip it into the cloned git repository.

We’d love to implement your improvements into Lead-DBS – please contact us for direct push access to Github or feel free to add pull-requests to the Lead-DBS repository.

Getting started

You can run Lead-DBS by typing "lead demo" into the Matlab prompt. This will open up the main GUI and a 3D viewer with an example patient. But there's much more to explore. Head over to our website to see a walkthrough tutorial, a manual, some more screenshots and other ressources. There's also a helpline in form of a Slack channel. We would love to hear from you.

Questions

If you have questions/problems when using Lead-DBS, you can checkout our: