Update change log and docs

bioforensics · Oct 23, 2023 · b98aaaf · b98aaaf
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diff --git a/CHANGELOG.md b/CHANGELOG.md
@@ -10,6 +10,9 @@ This project adheres to [Semantic Versioning](http://semver.org/).
 ### Changed
 - Merged RSIDs resolved during database build now propagated to the final marker definition (see #149).
 
+### Fixed
+- Added manual and automated fixes to ensure frequencies are formatted correcly and matche to the correct marker definition (see #150).
+
 
 ## [0.10.1] 2023-10-13
 

diff --git a/dbbuild/sources/yu2022g1/README.md b/dbbuild/sources/yu2022g1/README.md
@@ -40,10 +40,12 @@ mh06WL-068b,3,247,chr6,130615104,130615350,130615104;130615240;130615350,1309362
 
 Oddly, the marker mh06WL-069 is defined twice in Group 1, first at the locus chr6:32630944-32631142 and second at the locus chr6:108031328-108031471. The first definition perfectly matches the definition for mh06WL-017 in Group 2, both of which overlap with the marker mh06WL-037 defined in Group 4. The Group 1 definition for mh06WL-069 was updated to use the name mh06WL-017. The label mh06WL-037 ends up getting merged with mh06WL-017 in the final build.
 
+Also, we noted discrepancies between the RSIDs and the GRCh37 positions for the 32-SNP 199 bp definition at this locus. Accordingly, rs58770498 was manually replaced with rs17843724 and rs17843723 with rs17843723 to match the indicated positions in the original published definition for this marker.
+
 ```
 $ grep -e mh06WL-069 -e mh06WL-037 -e mh06WL-017 microhapdb/data/marker.csv
-mh06WL-017.v2,16,100,chr6,32663167,32663266,32663167;32663168;32663169;32663172;32663190;32663191;32663214;32663218;32663219;32663222;32663223;32663252;32663261;32663262;32663265;32663266,32630944;32630945;32630946;32630949;32630967;32630968;32630991;32630995;32630996;32630999;32631000;32631029;32631038;32631039;32631042;32631043,rs281863504;rs281863503;rs281863502;rs281863499;rs281863486;rs281863485;rs35986240;rs281863467;rs281863466;rs281863464;rs281863463;rs281863439;rs281863431;rs281863430;rs281863427;rs281863426,Yu2022G4
-mh06WL-017.v1,32,199,chr6,32663167,32663365,32663167;32663168;32663169;32663172;32663190;32663191;32663214;32663218;32663219;32663222;32663223;32663252;32663252;32663261;32663262;32663265;32663266;32663267;32663281;32663288;32663293;32663298;32663302;32663303;32663327;32663332;32663336;32663342;32663352;32663353;32663356;32663365,32630944;32630945;32630946;32630949;32630967;32630968;32630991;32630995;32630996;32630999;32631000;32631029;32631029;32631038;32631039;32631042;32631043;32631044;32631058;32631065;32631070;32631075;32631079;32631080;32631104;32631109;32631113;32631119;32631129;32631130;32631133;32631142,rs281863504;rs281863503;rs281863502;rs281863499;rs281863486;rs281863485;rs35986240;rs281863467;rs281863466;rs281863464;rs281863463;rs281863439;rs281863431;rs281863430;rs281863427;rs281863426;rs281863425;rs281863414;rs281863406;rs281863401;rs281863398;rs281863397;rs58770498;rs281863382;rs281863378;rs281863375;rs281863371;rs17843723;rs281863364;rs281863363;rs281863362;rs281863357,Yu2022G1;Yu2022G2
+mh06WL-017.v2,16,100,chr6,32663167,32663266,32663167;32663168;32663169;32663172;32663190;32663191;32663214;32663218;32663219;32663222;32663223;32663252;32663261;32663262;32663265;32663266,32630944;32630945;32630946;32630949;32630967;32630968;32630991;32630995;32630996;32630999;32631000;32631029;32631038;32631039;32631042;32631043,rs71542446;rs41270931;rs28724261;rs71542447;rs2854267;rs9274216;rs35986240;rs201930518;rs17613599;rs71542448;rs9274217;rs58770498;rs17613606;rs9274218;rs115495316;rs9274219,Yu2022G4
+mh06WL-017.v1,32,199,chr6,32663167,32663365,32663167;32663168;32663169;32663172;32663190;32663191;32663214;32663218;32663219;32663222;32663223;32663252;32663261;32663262;32663265;32663266;32663267;32663281;32663293;32663298;32663302;32663303;32663309;32663327;32663332;32663336;32663342;32663345;32663352;32663353;32663356;32663365,32630944;32630945;32630946;32630949;32630967;32630968;32630991;32630995;32630996;32630999;32631000;32631029;32631038;32631039;32631042;32631043;32631044;32631058;32631070;32631075;32631079;32631080;32631086;32631104;32631109;32631113;32631119;32631122;32631129;32631130;32631133;32631142,rs71542446;rs41270931;rs28724261;rs71542447;rs2854267;rs9274216;rs35986240;rs201930518;rs17613599;rs71542448;rs9274217;rs58770498;rs17613606;rs9274218;rs115495316;rs9274219;rs9274220;rs2856703;rs41270932;rs9274222;rs72844333;rs200098349;rs17843724;rs74222206;rs281863378;rs9274225;rs41270933;rs17613622;rs17613629;rs17613636;rs281863362;rs9274227,Yu2022G1;Yu2022G2
 mh06WL-069,3,144,chr6,107710124,107710267,107710124;107710141;107710267,108031328;108031345;108031471,rs9386660;rs539627870;rs2748441,Yu2022G1
 $ grep -e mh06WL-017 -e mh06WL-037 -e mh06WL-069 microhapdb/data/merged.csv 
 mh06WL-037,mh06WL-017