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Wu et al. 2021 #96

Merged
merged 6 commits into from
Nov 2, 2022
Merged

Wu et al. 2021 #96

merged 6 commits into from
Nov 2, 2022

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standage
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@standage standage commented Nov 1, 2022

This branch adds a new marker collection from Wu et al. (2021). Closes #94.

Effective number of alleles (Ae)

avg_ae_26_vs_3

This plot shows Ae values averaged over the three Chinese population groups in the 1000 Genomes Project as a function of Ae averaged over all 26 global population groups. Glyphs above the dashed grey line at y=x indicate markers with more allelic diversity in Chinese populations than the global average. Markers from this study are shown in red, with markers from USC and ALFRED shown in green and blue for comparison.

avg_ae_26_vs_chinese

This plot shows Ae values in three distinct Chinese population groups as a function of the global average Ae.

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standage commented Nov 1, 2022

Comment on lines -28 to +29
mh01NH-03 MHDBM-e7a95c5e GRCh38 chr1 184807944,184807966,184808042 1.9085 0.1987 0.1725 10.1016/j.legalmed.2015.06.003
mh01NH-03 MHDBM-e7a95c5e GRCh38 chr1 184807944,184807966,184808042 1.9086 0.1987 0.1725 10.1016/j.legalmed.2015.06.003
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@standage standage Nov 1, 2022

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A couple of these rounding artifacts pop up every once in a while depending on numpy or pandas version. 🤨

Comment on lines +49 to +51
rsid = fields[2]
if rsid not in rsids:
continue
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One of the markers is spanned by two CNVs, resulting in bookkeeping errors when aggregating the marker SNP data. These change to the build code eliminates that error.

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Will do this today!

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Looks good!

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standage commented Nov 2, 2022

Thanks @rnmitchell!

@standage standage merged commit 5134431 into master Nov 2, 2022
@standage standage deleted the wu2021 branch November 2, 2022 13:26
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Wu et al 2021
2 participants