Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Recognize MEI DELs with ALT format <DEL:ME> in SVAnnotate #8125

Merged
merged 2 commits into from Jan 3, 2023

Conversation

epiercehoffman
Copy link
Contributor

Updates

Some GATK-SV VCFs contain MEI deletions with ALT in the format DEL:ME:ALU or DEL:ME. This change will allow SVAnnotate to recognize and annotate those records as deletions.

Testing

  • Added unit test with MEI DEL
  • Ran all unit and integration tests for SVAnnotate

@codecov
Copy link

codecov bot commented Dec 8, 2022

Codecov Report

Merging #8125 (3eb4c98) into master (84ade40) will increase coverage by 40.209%.
The diff coverage is 100.000%.

Additional details and impacted files
@@               Coverage Diff                @@
##              master     #8125        +/-   ##
================================================
+ Coverage     46.436%   86.645%   +40.209%     
- Complexity     26473     38952     +12479     
================================================
  Files           2336      2336                
  Lines         182709    182710         +1     
  Branches       20060     20059         -1     
================================================
+ Hits           84843    158309     +73466     
+ Misses         91960     17366     -74594     
- Partials        5906      7035      +1129     
Impacted Files Coverage Δ
.../hellbender/tools/walkers/sv/SVAnnotateEngine.java 89.781% <100.000%> (-0.074%) ⬇️
...der/tools/walkers/sv/SVAnnotateEngineUnitTest.java 96.552% <100.000%> (+94.226%) ⬆️
...roadinstitute/hellbender/tools/LocalAssembler.java 67.425% <0.000%> (+0.073%) ⬆️
...r/tools/walkers/varianteval/VariantEvalEngine.java 84.040% <0.000%> (+0.249%) ⬆️
...itute/hellbender/utils/report/GATKReportTable.java 70.370% <0.000%> (+0.370%) ⬆️
...stitute/hellbender/utils/clipping/ReadClipper.java 74.138% <0.000%> (+0.575%) ⬆️
...lkers/annotator/allelespecific/AS_RankSumTest.java 87.195% <0.000%> (+0.610%) ⬆️
...kers/variantutils/PosteriorProbabilitiesUtils.java 81.875% <0.000%> (+0.625%) ⬆️
...stitute/hellbender/cmdline/CommandLineProgram.java 84.516% <0.000%> (+0.645%) ⬆️
...nstitute/hellbender/utils/read/AlignmentUtils.java 81.716% <0.000%> (+0.677%) ⬆️
... and 826 more

Copy link
Contributor

@mwalker174 mwalker174 left a comment

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

Great!

@epiercehoffman epiercehoffman merged commit 3687415 into master Jan 3, 2023
@epiercehoffman epiercehoffman deleted the eph_recognize_mei_del_svannotate branch January 3, 2023 20:57
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

None yet

2 participants