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[Response to Reviewers] add signature summary visualization #131

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merged 1 commit into from
Jul 14, 2023

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@gwaybio gwaybio commented Jul 14, 2023

bortezomib_signature_interpretation_summary

We will add to Figure 2-Supplement 4

Created in response to reviewer comment:

Reviewer 2 - Major Comment 7:
Next to feature importance, the authors do not discuss (or I missed) what biology the features represent. Such the reader is left wondering what the actual mechanism of bortezomib resistance could be and if cell painting could shed light on the molecular alterations that cause the treatment resistance. While reviewing, I thus wondered which audience the authors targeted with their manuscript. A more focused analysis of their data that highlights aspects of the study either for the machine learning community, the cell biology community, or the precision oncology community would greatly benefit the manuscript's impact. In its current form, the study's findings seem diluted and spread across a wide range of research questions.

@gwaybio gwaybio merged commit 90b9b62 into broadinstitute:master Jul 14, 2023
@gwaybio gwaybio deleted the signature-viz branch July 14, 2023 18:12
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