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clustNet: Network-based clustering with covariate adjustment

License: GPL v3

clustNet is an R package for network-based clustering of categorical data using a Bayesian network mixture model and optional covariate adjustment.

Installation

The package requires Rgraphviz and RBGL, which can be installed from Bioconductor as follows:

if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager")
BiocManager::install(c("Rgraphviz", "RBGL"))

The latest stable version of clustNet is available on CRAN and can be installed with

install.packages("clustNet")

from within an R session. On a normal computer, this should take around 5-60 seconds, depending on how many of the required packages are already installed.

BiocManager::install("remotes")

Being hosted on GitHub, it is also possible to use the install_github tool from an R session to install the latest development version:

library("devtools")
install_github("cbg-ethz/clustNet")

clustNet requires R >= 3.5.

Example

library(clustNet)

# Simulate data
k_clust <- 3 # numer of clusters
ss <- c(400, 500, 600) # samples in each cluster
simulation_data <- sampleData(k_clust = k_clust, n_vars = 20, n_samples = ss)
sampled_data <- simulation_data$sampled_data

# Network-based clustering
cluster_results <- get_clusters(sampled_data, k_clust = k_clust)

# Load additional pacakges to visualize the networks
library(ggplot2)
library(ggraph)
library(igraph)
library(ggpubr)

# Visualize networks
plot_clusters(cluster_results)

# Load additional pacakges to create a 2d dimensionality reduction
library(car)
library(ks)
library(graphics)
library(stats)

# Plot a 2d dimensionality reduction
density_plot(cluster_results)

On a normal computer, the clustering should take around 2-4 minutes.