Manual validation of regulated proteins in quantitative proteomics has always been a tedious process. Here we present Rover, a tool to facilitate this process. Rover accepts quantitative data from different sources such as Mascot Distiller and MaxQuant. In an intuitive environment, Rover visualizes the quantitative data in such a way that the user can select and validate proteins in comparisons to the whole experiment and in the context of the protein inference problem.
Colaert, N., Helsens, K., Impens, F., Vandekerckhove, J., Gevaert, K. (2010). Rover: a tool to visualize and validate quantitative proteomics data from different sources. Proteomics see PubMed.
Combination of different quantification can now also be done with Rover:
Colaert N, Van Huele C, Degroeve S, Staes A, Vandekerckhove J, Gevaert K, Martens L. Combining quantitative proteomics data processing workflows for greater sensitivity. Nat Methods. see PubMed.
You can find the latest version here.
The rover project is grateful for the support by: