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Releases: cpicpgx/cpic-data

v1.22.2

03 Feb 18:53
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1.22.2 (2023-02-03)

⚠️ Reversion ⚠️

Bug Fixes

  • fix frequency exporter to not show null allele data (79745ba)

v1.22.1

31 Jan 20:05
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1.22.1 (2023-01-31)

Bug Fixes

  • [fluorouracil & capecitabine] [RECOMMENDATION] Fixed the Therapeutic Recommendation text for Activity Score 1.5 to match the published guideline
  • properly encode spaces in filenames uploaded to S3 (1394d80)

Updates

  • [simvastatin-CYP3A4] PharmGKB level changed from none to 3
  • [atorvastatin-CYP3A5] PharmGKB level changed from none to 3
  • [atorvastatin-CYP3A4] PharmGKB level changed from none to 3
  • [lovastatin-HMGCR] PharmGKB level changed from none to 3
  • [rosuvastatin-CYP3A5] PharmGKB level changed from none to 3
  • [lovastatin-CYP3A5] PharmGKB level changed from none to 3
  • [simvastatin-CYP3A5] PharmGKB level changed from none to 4
  • [tacrolimus-CYP3A4] PharmGKB level changed from 1B to 2A
  • [fluvastatin-HMGCR] PharmGKB level changed from none to 3
  • [fluvastatin-CYP3A4] PharmGKB level changed from none to 3
  • [atorvastatin-HMGCR] PharmGKB level changed from none to 3
  • [tolbutamide-G6PD] PGx testing level changed from none to Actionable PGx
  • [mivacurium-BCHE] PGx testing level changed from none to Actionable PGx
  • [trametinib-G6PD] PGx testing level changed from none to Informative PGx
  • [tolazamide-G6PD] PGx testing level changed from none to Actionable PGx
  • [capecitabine-DPYD] PGx testing level changed from Actionable PGx to Testing recommended

v1.22.0

27 Jan 03:45
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1.22.0 (2023-01-27)

Features

  • updated to PharmVar version 5.2.17 with an update to CYP4F2
  • add new make script for copying the DB (e9ebb6a)

Bug Fixes

v1.21.6

21 Dec 02:10
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1.21.6 (2022-12-21)

Bug Fixes

v1.21.5

20 Dec 02:06
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1.21.5 (2022-12-20)

Bug Fixes

v1.21.4

20 Dec 01:58
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1.21.4 (2022-12-20)

Bug Fixes

v1.21.3

31 Oct 21:16
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1.21.3 (2022-10-31)

Features

  • updated to support PharmVar version 5.2.11

Bug Fixes

  • remove unneeded data caching scripts (3cf620d)
  • fix function assignment for G6PD allele function reference file

v1.21.2

24 Oct 18:40
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1.21.2 (2022-10-24)

Bug Fixes

  • fix population summary stats on frequency export sheets (d4c13f8)

v1.21.1

20 Oct 23:03
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1.21.1 (2022-10-20)

Bug Fixes

  • move B allele to top of G6PD allele function file so it becomes the inferred frequency
  • change primaquine to use only one population
  • normalize "general" population sheet name
  • normalize "Malignant Hyperthermia" casing
  • put CYP4F2 *3 mention in warfarin diagram
  • do not generate diplotype/phenotype frequencies for x-linked genes (8f4a7d9)
  • normalize user-generated function descriptions (ca8846d)
  • put CYP4F2 *3 mention in warfarin diagram (d0f57d4)

v1.21.0

04 Oct 23:14
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1.21.0 (2022-10-04)

Features

  • update from PharmVar for CYP2C19
  • new data for the just-published G6PD guideline
  • add drug flowcharts for G6PD drugs (42c750f)

Bug Fixes

  • add pointer to fosphenytoin flow chart (f395963)
  • fix ordering bug for variants in PharmCAT export (795cafa)
  • standardize activity values and scores to always use decimal format (4e458f4)