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43 changes: 40 additions & 3 deletions README.rst
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@@ -1,9 +1,11 @@
.. image:: https://zenodo.org/badge/21196/maxplanck-ie/HiCExplorer.svg
:target: https://zenodo.org/badge/latestdoi/21196/maxplanck-ie/HiCExplorer

.. image:: https://travis-ci.org/maxplanck-ie/HiCExplorer.svg?branch=master
:target: https://travis-ci.org/maxplanck-ie/HiCExplorer
.. image:: https://readthedocs.org/projects/hicexplorer/badge/?version=docs
:target: http://hicexplorer.readthedocs.io/?badge=docs
.. image:: https://anaconda.org/bioconda/hicexplorer/badges/installer/conda.svg
:target: https://anaconda.org/bioconda/hicexplorer

.. image:: https://quay.io/repository/biocontainers/hicexplorer/status
:target: https://quay.io/repository/biocontainers/hicexplorer

Expand All @@ -21,8 +23,43 @@ long-range contacts. Moreover, it allows the visualization of multiple contact m
data like genes, compartments, ChIP-seq coverage tracks (and in general any type of genomic scores) and long range contacts.


Citation:
^^^^^^^^^

Fidel Ramirez, Vivek Bhardwaj, Jose Villaveces, Laura Arrigoni, Bjoern A Gruening, Kin Chung Lam, Bianca Habermann, Asifa Akhtar, Thomas Manke
**"High-resolution TADs reveal DNA sequences underlying genome organization in flies"**. bioRxiv 115063; doi: https://doi.org/10.1101/115063

.. image:: ./docs/images/hicex2.png

Installation
^^^^^^^^^^^^

HiCExplorer is available for:

- Command line usage (via pip/anaconda/github)
- Integration into Galaxy servers (via toolshed/API/web-browser)

There are many easy ways to install HiCExplorer. Details can be found
`here <https://http://hicexplorer.readthedocs.io/content/installation.html>`__

**Install by cloning this repository:**

You can install any one of the HiCExplorer branches on command line
(linux/mac) by cloning this git repository:

::

$ git clone https://github.com/maxplanck-ie/HiCExplorer.git
$ cd HiCExplorer
$ python setup.py install

If you don't have root permission, you can set a specific folder using the ``--prefix`` option

::

$ python setup.py install --prefix /User/Tools/hicexplorer


For more the complete documentation visit `<http://hicexplorer.readthedocs.org/>`_
Documentation:
^^^^^^^^^^^^^^
Please visit our complete documentation `Here <http://hicexplorer.readthedocs.org/>`_
2 changes: 1 addition & 1 deletion docs/conf.py
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Expand Up @@ -77,7 +77,7 @@
def get_version():
import re
try:
f = open("../deeptools/_version.py")
f = open("../hicexplorer/_version.py")
except EnvironmentError:
return None
for line in f.readlines():
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43 changes: 43 additions & 0 deletions docs/content/News.rst
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News and Developments
=====================


Preprint introducing HiCExplorer is now online
----------------------------------------------

**March 8, 2017**

Our #biorXiv preprint on DNA sequences behind Fly genome architecture is online!

Read the article here : `<http://biorxiv.org/content/early/2017/03/08/115063>`_

In this article, we introduce HiCExplorer : Our easy to use tool for HiC data analysis, also available in `Galaxy <https://galaxyproject.org/>`_.

We also introduce `HiCBrowser <https://github.com/maxplanck-ie/HiCBrowser>`_ : A standalone software to visualize HiC along with other genomic datasets.

Based on HiCExplorer and HiCBrowser, we built a useful resource for anyone to browse and download the chromosome
conformation datasets in Human, Mouse and Flies. It's called `the chorogenome navigator <http://chorogenome.ie-freiburg.mpg.de/>`_

Along with these resources, we present an analysis of DNA sequences behind 3D genome of Flies. Using high-resolution
HiC analysis, we find a set of DNA motifs that characterize TAD boundaries in Flies and show the importance of these motifs in genome organization.

We hope that these resources and analysis would be useful for the community and welcome any feedback.


HiCExplorer wins best poster prize at VizBi2016
-----------------------------------------------

**March 20, 2016**

We are excited to announce that HiCExplorer has won
the `NVIDIA Award for Best Scientific Poster <https://vizbi.org/blog/2016/02/11/nvidia-award-for-best-scientific-poster/>`_
in VizBi2016, the international conference on visualization of biological data.

`Read more here <https://vizbi.org/blog/2016/03/20/winner-of-nvidia-best-scientific-poster-award-2/>`_

This was our poster :

.. image:: https://vizbi.org/Posters/Images/2016/B12.png
:scale: 50 %
:alt: HiCExplorer
:align: left
40 changes: 34 additions & 6 deletions docs/content/installation.rst
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Expand Up @@ -8,12 +8,14 @@ Requirements
-------------

* Python 2.7
* numpy >= 1.8.1
* scipy >= 0.14.0
* numpy >= 1.10.4
* scipy >= 0.17.1
* matplotlib >= 1.5.3
* pysam >= 0.8.3
* matplotlib >= 1.3.1
* bx-python >= 0.7.1
* intervaltree >= 2.1.0
* biopython >= 1.65
* tables >= 3.2.2
* pyBigWig >=0.2.8

The fastet way to obtain **Python 2.7 together with numpy and scipy** is
via the `Anaconda Scientific Python
Expand All @@ -23,7 +25,7 @@ follow the directions for its installation. All of the requirements for HiCExplo

.. code:: bash
$ conda install -c bioconda hicexplorer=0.1
$ conda install hicexplorer=1.6 -c bioconda -c conda-forge
Command line installation using ``pip``
-----------------------------------------
Expand Down Expand Up @@ -54,8 +56,34 @@ You are highly recommended to use `pip` rather than these more complicated steps

$ git clone https://github.com/maxplanck-ie/HiCExplorer.git

3. install the source code (if you don't have root permission, you can set
or if you want a particular release, choose one from https://github.com/maxplanck-ie/HiCExplorer/releases:
::

$ wget https://github.com/maxplanck-ie/HiCExplorer/archive/1.5.12.tar.gz
$ tar -xzvf

3. To install the source code (if you don't have root permission, you can set
a specific folder using the ``--prefix`` option)
::

$ python setup.py install --prefix /User/Tools/hicexplorer


Galaxy installation
--------------------

HiCExplorer can be easily integrated into a local `Galaxy <http://galaxyproject.org>`_.

Installation with Docker
^^^^^^^^^^^^^^^^^^^^^^^^

The HiCExplorer Galaxy instance is also available as a docker container, for those wishing to use the Galaxy
framework but who also prefer a virtualized solution. This container is quite simple to install:

::

$ sudo docker pull quay.io/bgruening/galaxy-hicexplorer

To start and otherwise modify this container, please see the instructions on `the docker-galaxy-stable github repository <https://github.com/bgruening/docker-galaxy-stable>`__. Note that you must use `bgruening/galaxy-deeptools` in place of `bgruening/galaxy-stable` in the examples, as the deepTools Galaxy container is built on top of the galaxy-stable container.

.. tip:: For support, or feature requests contact: deeptools@googlegroups.com
28 changes: 15 additions & 13 deletions docs/index.rst
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Expand Up @@ -32,16 +32,12 @@ tool description
=============================== ===========================================================================================


Mailing list
Getting Help
------------

If you have questions, requests, or bugs to report, please email the
`deepTools mailing list <https://groups.google.com/forum/#!forum/deeptools>`_



This tool suite is developed by the `Bioinformatics Unit <http://www.ie-freiburg.mpg.de/bioinformaticsfac>`_
at the `Max Planck Institute for Immunobiology and Epigenetics <http://www.ie-freiburg.mpg.de/>`_, Freiburg.
* For general questions, please use Biostars with Tag `hicexplorer` : `Biostars <https://www.biostars.org/t/hicexplorer/>`_
* For specific questions and feature requests, use the `deepTools mailing list <https://groups.google.com/forum/#!forum/deeptools>`_
* For suggesting changes/enhancements and to report bugs, please create an issue on `our GitHub repository <https://github.com/maxplanck-ie/HiCExplorer>`_


Contents:
Expand All @@ -53,11 +49,17 @@ Contents:
content/installation
content/list-of-tools
content/example_usage
content/News

Citation
---------

Please cite HiCExplorer as follows:

Fidel Ramirez, Vivek Bhardwaj, Jose Villaveces, Laura Arrigoni, Bjoern A Gruening,Kin Chung Lam, Bianca Habermann, Asifa Akhtar, Thomas Manke.
**"High-resolution TADs reveal DNA sequences underlying genome organization in flies". bioRxiv 115063** doi: https://doi.org/10.1101/115063

Indices and tables
==================
.. image:: images/logo_mpi-ie.jpg

* :ref:`genindex`
* :ref:`modindex`
* :ref:`search`
This tool suite is developed by the `Bioinformatics Unit <http://www.ie-freiburg.mpg.de/bioinformaticsfac>`_
at the `Max Planck Institute for Immunobiology and Epigenetics <http://www.ie-freiburg.mpg.de/>`_, Freiburg.
4 changes: 2 additions & 2 deletions setup.py
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Expand Up @@ -92,8 +92,8 @@ def checkProgramIsInstalled(self, program, args, where_to_download,
setup(
name='HiCExplorer',
version=get_version(),
author='Fidel Ramirez',
author_email='ramirez@ie-freiburg.mpg.de',
author='Fidel Ramirez, Vivek Bhardwaj, Björn Grüning',
author_email='deeptools@googlegroups.com',
packages=['hicexplorer'],
scripts=['bin/findRestSite', 'bin/hicBuildMatrix', 'bin/hicCorrectMatrix',
'bin/hicCorrelate', 'bin/hicFindEnrichedContacts', 'bin/hicFindTADs',
Expand Down

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