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Using CNVkit with THetA2 and "Sample_paired.vcf"? #882

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ngs-seqer opened this issue May 13, 2024 · 0 comments
Open

Using CNVkit with THetA2 and "Sample_paired.vcf"? #882

ngs-seqer opened this issue May 13, 2024 · 0 comments

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@ngs-seqer
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ngs-seqer commented May 13, 2024

Hi,

I use the pooled and not-matched normal samples to run cnvkit and now I want to create *interval_count, *tumor.snp_formatted.txt and *normal.snp_formatted.txt to run THetA2.

I found this example in your manual:

cnvkit.py export theta Sample_T.cns reference.cnn -v Sample_Paired.vcf

I can locate *cns and reference.cnn files generated from the CNVkit-batch mode, but where is this "Sample-Paired.vcf"? or How can I generate this vcf file?

Could you provide some example codes showing how to get this vcf file?

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