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function [segmentation] = ft_datatype_segmentation(segmentation, varargin)
% FT_DATATYPE_SEGMENTATION describes the FieldTrip MATLAB structure for segmented
% voxel-based data and atlasses. A segmentation can either be indexed or
% probabilistic (see below).
%
% A segmentation is a volumetric description which is usually derived from an
% anatomical MRI, which describes for each voxel the tissue type. It for example
% distinguishes between white matter, grey matter, csf, skull and skin. It is mainly
% used for masking in visualization, construction of volume conduction models and for
% construction of cortical sheets. An volume-based atlas is basically a very detailed
% segmentation with an anatomical label for each voxel.
%
% For example, the AFNI TTatlas+tlrc segmented brain atlas (which can be created
% with FT_READ_ATLAS) looks like this
%
% dim: [161 191 141] the size of the 3D volume in voxels
% transform: [4x4 double] affine transformation matrix for mapping the voxel coordinates to head coordinate system
% coordsys: 'tal' the transformation matrix maps the voxels into this (head) coordinate system
% unit: 'mm' the units in which the coordinate system is expressed
% brick0: [161x191x141 uint8] integer values from 1 to N, the value 0 means unknown
% brick1: [161x191x141 uint8] integer values from 1 to M, the value 0 means unknown
% brick0label: {Nx1 cell}
% brick1label: {Mx1 cell}
%
% An example segmentation with binary values that can be used for construction of a
% BEM volume conduction model of the head looks like this
%
% dim: [256 256 256] the dimensionality of the 3D volume
% transform: [4x4 double] affine transformation matrix for mapping the voxel coordinates to head coordinate system
% coordsys: 'ctf' the transformation matrix maps the voxels into this (head) coordinate system
% unit: 'mm' the units in which the coordinate system is expressed
% brain: [256x256x256 logical] binary map representing the voxels which belong to the brain
% skull: [256x256x256 logical] binary map representing the voxels which belong to the skull
% scalp: [256x256x256 logical] binary map representing the voxels which belong to the scalp
%
% An example of a whole-brain anatomical MRI that was segmented using FT_VOLUMESEGMENT
% looks like this
%
% dim: [256 256 256] the size of the 3D volume in voxels
% transform: [4x4 double] affine transformation matrix for mapping the voxel coordinates to head coordinate system
% coordsys: 'ctf' the transformation matrix maps the voxels into this (head) coordinate system
% unit: 'mm' the units in which the coordinate system is expressed
% gray: [256x256x256 double] probabilistic map of the gray matter
% white: [256x256x256 double] probabilistic map of the white matter
% csf: [256x256x256 double] probabilistic map of the cerebrospinal fluid
%
% The examples above demonstrate that a segmentation can be indexed, i.e. consisting
% of subsequent integer numbers (1, 2, ...) or probabilistic, consisting of real
% numbers ranging from 0 to 1 that represent probabilities between 0% and 100%. An
% extreme case is one where the probability is either 0 or 1, in which case the
% probability can be represented as a binary or logical array.
%
% The only difference to the volume data representation is that the segmentation
% structure contains the additional fields xxx and xxxlabel. See FT_DATATYPE_VOLUME
% for further details.
%
% Required fields:
% - dim, transform
%
% Optional fields:
% - brain, skull, scalp, gray, white, csf, or any other field with dimensions that are consistent with dim
% - unit, coordsys, fid
%
% Deprecated fields:
% - none
%
% Obsoleted fields:
% - none
%
% Revision history:
% (2012/latest) The explicit distunction between the indexed and probabilistic
% representation was made. For the indexed representation the additional
% xxxlabel cell-array was introduced.
%
% (2005) The initial version was defined.
%
% See also FT_DATATYPE, FT_DATATYPE_VOLUME, FT_DATATYPE_PARCELLATION
% Copyright (C) 2012, Robert Oostenveld
%
% This file is part of FieldTrip, see http://www.fieldtriptoolbox.org
% for the documentation and details.
%
% FieldTrip is free software: you can redistribute it and/or modify
% it under the terms of the GNU General Public License as published by
% the Free Software Foundation, either version 3 of the License, or
% (at your option) any later version.
%
% FieldTrip is distributed in the hope that it will be useful,
% but WITHOUT ANY WARRANTY; without even the implied warranty of
% MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
% GNU General Public License for more details.
%
% You should have received a copy of the GNU General Public License
% along with FieldTrip. If not, see <http://www.gnu.org/licenses/>.
%
% $Id$
% get the optional input arguments, which should be specified as key-value pairs
version = ft_getopt(varargin, 'version', 'latest');
segmentationstyle = ft_getopt(varargin, 'segmentationstyle'); % can be indexed or probabilistic
hasbrain = ft_getopt(varargin, 'hasbrain', 'no'); % no means that it is not required, if present it won't be removed
% convert from string into boolean
hasbrain = istrue(hasbrain);
if strcmp(version, 'latest')
segversion = '2012';
volversion = 'latest';
clear version
else
segversion = version;
volversion = version;
clear version
end
if isempty(segmentation)
return;
end
switch segversion
case '2012'
% convert the inside/outside fields, they should be logical rather than an index
if isfield(segmentation, 'inside')
segmentation = fixinside(segmentation, 'logical');
end
% make a list of fields that possibly represent a segmentation
fn = fieldnames(segmentation);
fn = setdiff(fn, 'inside'); % exclude the inside field from any conversions
sel = false(size(fn));
for i=1:numel(fn)
sel(i) = (isnumeric(segmentation.(fn{i})) || islogical(segmentation.(fn{i}))) && numel(segmentation.(fn{i}))==prod(segmentation.dim(1:3));
end
% only consider numeric fields of the correct size
fn = fn(sel);
% determine whether the style of the input fields is probabilistic or indexed
[indexed, probabilistic] = determine_segmentationstyle(segmentation, fn, segmentation.dim(1:3));
% ignore the fields that do not contain a segmentation
sel = indexed | probabilistic;
fn = fn(sel);
indexed = indexed(sel);
probabilistic = probabilistic(sel);
% convert from an exclusive to cumulative representation
% this is only only for demonstration purposes
% for i=1:length(sel)
% segmentation.(fn{sel(i)}) = volumefillholes(segmentation.(fn{sel(i)}));
% end
[dum, i] = intersect(fn, {'scalp', 'skull', 'brain'});
if numel(i)==3
% put them in the preferred order
fn(i) = {'scalp', 'skull', 'brain'};
end
[dum, i] = intersect(fn, {'skin', 'skull', 'brain'}); % this is not likely
if numel(i)==3
% put them in the preferred order
fn(i) = {'skin', 'skull', 'brain'};
end
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
% ensure that the segmentation is internally consistent
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
if any(probabilistic)
segmentation = fixsegmentation(segmentation, fn(probabilistic), 'probabilistic');
end
if any(indexed)
segmentation = fixsegmentation(segmentation, fn(indexed), 'indexed');
end
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
% convert the segmentation to the desired style
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
if isempty(segmentationstyle)
% keep it as it is
elseif strcmp(segmentationstyle, 'indexed') && any(probabilistic)
segmentation = convert_segmentationstyle(segmentation, fn(probabilistic), segmentation.dim, 'indexed');
indexed(probabilistic) = true; % these are now indexed
probabilistic(probabilistic) = false; % these are now indexed
elseif strcmp(segmentationstyle, 'probabilistic') && any(indexed)
segmentation = convert_segmentationstyle(segmentation, fn(indexed), segmentation.dim, 'probabilistic');
probabilistic(indexed) = true; % these are now probabilistic
indexed(indexed) = false; % these are now probabilistic
end % converting between probabilistic and indexed
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
% add the brain if requested
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
if hasbrain
if all(indexed)
fn = fieldnames(segmentation);
sel = false(size(fn));
for i=1:numel(fn)
sel(i) = any(strcmp(fn, [fn{i} 'label']));
end
fn = fn(sel);
if numel(fn)>1
ft_error('cannot construct a brain mask on the fly; this requires a single indexed representation');
else
tissue = segmentation.(fn{1});
tissuelabel = segmentation.([fn{1} 'label']);
if ~any(strcmp(tissuelabel, 'brain'))
threshold = 0.5;
smooth = 5;
% ensure that the segmentation contains the brain mask, if not then construct it from gray+white+csf
if ~all(ismember({'gray' 'white' 'csf'}, tissuelabel))
ft_error('cannot construct a brain mask on the fly; this requires gray, white and csf');
end
gray = tissue==find(strcmp(tissuelabel, 'gray'));
white = tissue==find(strcmp(tissuelabel, 'white'));
csf = tissue==find(strcmp(tissuelabel, 'csf'));
brain = gray + white + csf;
clear gray white csf seg
brain = volumesmooth(brain, smooth, 'brain');
brain = volumethreshold(brain, threshold, 'brain');
% store it in the output
segmentation.brain = brain;
end % try to construct the brain
end % if single indexed representation
elseif all(probabilistic)
if ~isfield(segmentation, 'brain')
if ~all(isfield(segmentation, {'gray' 'white' 'csf'}))
ft_error('cannot construct a brain mask on the fly; this requires gray, white and csf');
end
threshold = 0.5;
smooth = 5;
% ensure that the segmentation contains the brain mask, if not then construct it from gray+white+csf tissue probability maps
fprintf('creating brainmask ... using the sum of gray, white and csf tpms\n');
brain = segmentation.gray + segmentation.white + segmentation.csf;
brain = volumesmooth(brain, smooth, 'brain');
brain = volumethreshold(brain, threshold, 'brain');
% store it in the output
segmentation.brain = brain;
end
else
ft_error('cannot construct a brain mask on the fly; this requires a uniquely indexed or probabilitic representation');
end
end % if hasbrain
case '2005'
% the only difference is that the indexed representation for xxx did not have the xxxlabel field prior to the 2012 version
fn = fieldnames(segmentation);
sel = ~cellfun(@isempty, regexp(fn, 'label$'));
segmentation = rmfield(segmentation, fn(sel));
% furthermore it corresponds to the oldest version of the volume representation
volversion = '2003';
otherwise
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
ft_error('unsupported version "%s" for segmentation datatype', segversion);
end
% the segmentation is a special type of volume structure, so ensure that it also fulfills the requirements for that
segmentation = ft_datatype_volume(segmentation, 'version', volversion);
% For the pass through ft_datatype_volume it is perhaps necessary to remove
% the fields that are specific for the segmentation and add them later again.
% At this moment ft_datatype_volume nicely passes all fields, so there is no
% special handling of the segmentation fields needed.