obsoleted term fixes #22203

src/ontology/go-edit.obo

@@ -229481,11 +229481,13 @@ property_value: term_tracker_item https://github.com/geneontology/go-ontology/is
 
 [Term]
 id: GO:0040030
-name: regulation of molecular function, epigenetic
+name: obsolete regulation of molecular function, epigenetic
 namespace: biological_process
-def: "Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:ems, GOC:tb, PMID:10611975, PMID:11050225, PMID:11447696, PMID:11685242, PMID:11782551]
+def: "OBSOLETE. Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:ems, GOC:tb, PMID:10611975, PMID:11050225, PMID:11447696, PMID:11685242, PMID:11782551]
+comment: This term was obsoleted because it is not an active process.
 synonym: "regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb]
-is_a: GO:0065009 ! regulation of molecular function
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22203 xsd:anyURI
+is_obsolete: true
 
 [Term]
 id: GO:0040031
@@ -266640,30 +266642,32 @@ intersection_of: positively_regulates GO:0045451 ! pole plasm oskar mRNA localiz
 
 [Term]
 id: GO:0045857
-name: negative regulation of molecular function, epigenetic
+name: obsolete negative regulation of molecular function, epigenetic
 namespace: biological_process
-def: "Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb]
+def: "OBSOLETE. Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb]
+comment: This term was obsoleted because it is not an active process.
 synonym: "down regulation of protein activity, epigenetic" EXACT []
 synonym: "down-regulation of protein activity, epigenetic" EXACT []
 synonym: "downregulation of protein activity, epigenetic" EXACT []
 synonym: "inhibition of protein activity, epigenetic" NARROW []
 synonym: "negative regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb]
-is_a: GO:0040030 ! regulation of molecular function, epigenetic
-is_a: GO:0044092 ! negative regulation of molecular function
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22203 xsd:anyURI
+is_obsolete: true
 
 [Term]
 id: GO:0045858
-name: positive regulation of molecular function, epigenetic
+name: obsolete positive regulation of molecular function, epigenetic
 namespace: biological_process
-def: "Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb]
+def: "OBSOLETE. Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya." [GOC:dph, GOC:go_curators, GOC:tb]
+comment: This term was obsoleted because it is not an active process.
 synonym: "activation of protein activity, epigenetic" NARROW []
 synonym: "positive regulation of protein activity, epigenetic" EXACT [GOC:dph, GOC:tb]
 synonym: "stimulation of protein activity, epigenetic" NARROW []
 synonym: "up regulation of protein activity, epigenetic" EXACT []
 synonym: "up-regulation of protein activity, epigenetic" EXACT []
 synonym: "upregulation of protein activity, epigenetic" EXACT []
-is_a: GO:0040030 ! regulation of molecular function, epigenetic
-is_a: GO:0044093 ! positive regulation of molecular function
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22203 xsd:anyURI
+is_obsolete: true
 
 [Term]
 id: GO:0045859
@@ -375927,6 +375931,7 @@ synonym: "ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah]
 synonym: "ribonucleoprotein complex nucleus export" EXACT [GOC:mah]
 synonym: "ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah]
 synonym: "RNP export from nucleus" EXACT [GOC:mah]
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22246 xsd:anyURI
 is_obsolete: true
 created_by: mah
 creation_date: 2009-12-16T10:13:01Z
@@ -375941,6 +375946,7 @@ synonym: "mRNA-containing ribonucleoprotein complex export from cell nucleus" EX
 synonym: "mRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah]
 synonym: "mRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah]
 synonym: "mRNA-containing RNP export from nucleus" EXACT [GOC:mah]
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22246 xsd:anyURI
 is_obsolete: true
 consider: GO:0006406
 created_by: mah
@@ -375956,6 +375962,7 @@ synonym: "rRNA-containing ribonucleoprotein complex export from cell nucleus" EX
 synonym: "rRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah]
 synonym: "rRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah]
 synonym: "rRNA-containing RNP export from nucleus" EXACT [GOC:mah]
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22246 xsd:anyURI
 is_obsolete: true
 created_by: mah
 creation_date: 2009-12-16T10:15:07Z
@@ -375965,11 +375972,12 @@ id: GO:0071429
 name: obsolete snRNA-containing ribonucleoprotein complex export from nucleus
 namespace: biological_process
 def: "OBSOLETE. The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm." [GOC:mah]
-comment: This term has been obsoleted because it represents a process and its substrate.
+comment: This term has been obsoleted because it represents the transport of a carrier bound to its substrate.
 synonym: "snRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah]
 synonym: "snRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah]
 synonym: "snRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah]
 synonym: "snRNA-containing RNP export from nucleus" EXACT [GOC:mah]
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22246 xsd:anyURI
 is_obsolete: true
 created_by: mah
 creation_date: 2009-12-16T10:15:38Z
@@ -375979,12 +375987,13 @@ id: GO:0071430
 name: obsolete pre-miRNA-containing ribonucleoprotein complex export from nucleus
 namespace: biological_process
 def: "OBSOLETE. The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm." [GOC:mah, GOC:sl]
-comment: This term has been obsoleted because it represents a process and its substrate.
+comment: This term has been obsoleted because it represents the transport of a carrier bound to its substrate.
 synonym: "pre-microRNA-containing ribonucleoprotein complex export from cell nucleus" EXACT [GOC:mah]
 synonym: "pre-microRNA-containing ribonucleoprotein complex export from nucleus" EXACT []
 synonym: "pre-microRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah]
 synonym: "pre-microRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah]
 synonym: "pre-microRNA-containing RNP export from nucleus" EXACT [GOC:mah]
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22246 xsd:anyURI
 is_obsolete: true
 created_by: mah
 creation_date: 2009-12-16T10:26:16Z
@@ -375999,6 +376008,7 @@ synonym: "tRNA-containing ribonucleoprotein complex export from cell nucleus" EX
 synonym: "tRNA-containing ribonucleoprotein complex nucleus export" EXACT [GOC:mah]
 synonym: "tRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm" EXACT [GOC:mah]
 synonym: "tRNA-containing RNP export from nucleus" EXACT [GOC:mah]
+property_value: term_tracker_item https://github.com/geneontology/go-ontology/issues/22246 xsd:anyURI
 is_obsolete: true
 consider: GO:0051168
 created_by: mah