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all: $(subst .tex,.pdf.open,$(wildcard *.tex)) | ||
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%.pdf: %.tex | ||
pdflatex -shell-escape $< >$@ | ||
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%.open: % | ||
open $* | ||
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.SECONDARY: |
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\documentclass[10pt]{article} | ||
\begin{document} | ||
\title{BioE241 Homework 1} | ||
\date{} | ||
\maketitle | ||
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\begin{enumerate} | ||
\item Prove that the detailed balance condition for reversibility of a homogeneous continuous-time discrete-state Markov chain implies the existence of a symmetric matrix that is related to the instantaneous rate matrix by a similarity transformation. | ||
\item Prove that the matrix exponential, as defined by Taylor series, is a valid solution for the transition probabilities of a continuous-time discrete-state Markov chain. | ||
\item Prove that a continuous-time finite-state Markov chain necessarily has (at least) one equilibrium probability distribution over states. Under what conditions does it have more than one such distribution? Give an example. | ||
\end{enumerate} | ||
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\end{document} |