Error in Generating multi-resolution .mcool file

[AnakimG]

Hi @js2264,

When running the HiCool function like that :
x <- HiCool(
r1 = './MKL30_Merged_R1.fastq.gz',
r2 = './MKL30_Merged_R2.fastq.gz',
restriction = 'HpaII',
resolutions = c(500, 1000, 2000, 5000, 10000),
genome = './genome_SL1344.fasta',
output = './HiCool_MKL30_Merged/'
)

I get this error :
HiCool :: Generating multi-resolution .mcool file...
Error in py_call_impl(callable, call_args$unnamed, call_args$named) :
TypeError: 'int' object is not iterable
Run reticulate::py_last_error() for details.
Calls: HiCool ... -> force -> -> py_call_impl
Execution halte

I feel like it is a fastq files problem, because on certain fastq files it works and on others it doesn't.
Do you have any clue ?
Thanks in advance

Anakim

[js2264]

Hi @AnakimG, sorry I have no idea where this issue could originate from. The fastq files that work come from the same source that MKL30 reads? If two fastq files are corrupted and do not have identical # of reads, this could perhaps lead to such issue?