This is version 1.1.1 of EDGE Bioinformatics, a product of Los Alamos National Laboratory, Naval Medical Research Center, and the Defense Threat Reduction Agency.
EDGE is a highly adaptable bioinformatics platform that allows laboratories to quickly analyze and interpret genomic sequence data. The bioinformatics platform allows users to address a wide range of use cases including assay validation and the characterization of novel biological threats, clinical samples, and complex environmental samples.
A demonstration version of EDGE is currently available at https://bioedge.lanl.gov/ with example data sets available to the public to view and/or re-run and also allows EDGE runs of SRA/ENA data. (This webserver does not currently support upload of data due in part to LANL security regulations, however local installations are meant to be fully functional.) To run EDGE follow the "GUI" instructions from our documentation, found at https://edge.readthedocs.org/en/v1.1/introduction.html. It is also linked at the bottom of the EDGE homepage.
For basic information about EDGE, visit the EDGE ABC's, that provide a brief overview of EDGE, the various workflows, and the computational environment restraints for local use.
Chien-Chi Lo: chienchi@lanl.gov
Paul Li: po-e@lanl.gov
Joe Anderson (DTRA/NMRC): joseph.j.anderson2.civ@mail.mil
Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform
Po-E Li; Chien-Chi Lo; Joseph J. Anderson; Karen W. Davenport; Kimberly A. Bishop-Lilly; Yan Xu; Sanaa Ahmed; Shihai Feng; Vishwesh P. Mokashi; Patrick S.G. Chain
Nucleic Acids Research 2016;
[doi: 10.1093/nar/gkw1027] (http://nar.oxfordjournals.org/content/early/2016/11/28/nar.gkw1027.abstract?keytype=ref&ijkey=KzcEnQzdYkdjPCU)
Copyright (2013). Triad National Security, LLC. All rights reserved.
This program was produced under U.S. Government contract 89233218CNA000001 for Los Alamos National Laboratory (LANL), which is operated by Triad National Security, LLC for the U.S. Department of Energy/National Nuclear Security Administration.
All rights in the program are reserved by Triad National Security, LLC, and the U.S. Department of Energy/National Nuclear Security Administration. The Government is granted for itself and others acting on its behalf a nonexclusive, paid-up, irrevocable worldwide license in this material to reproduce, prepare derivative works, distribute copies to the public, perform publicly and display publicly, and to permit others to do so.
This is open source software; you can redistribute it and/or modify it under the terms of the GPLv3 License. If software is modified to produce derivative works, such modified software should be clearly marked, so as not to confuse it with the version available from LANL. Full text of the GPLv3 License can be found in the License file in the main development branch of the repository.