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cgMLST-comparison

Comparing distances for cgMLST

Methods

  1. Survey different cgMLST methods
  2. Have an existential crisis that each cgMLST method has a slightly different database that I cannot account for
  3. Receive validation datasets from PulseNet (not publicly available)
  4. Run cgMLST using each method
  5. Create pairwise distances using distance.* methods in the lskScripts repo
  6. Record
    • number of alleles in common
    • number of loci compared
    • identity = alleles / loci

Results

  1. Found suitable callers
    • EToKi
    • ChewBBACA
    • ColorID
  2. Created scatter plots with goodness of fit
dataset link
S. enterica notebook
L. monocytogenes notebook
C. jejuni notebook
E. coli notebook

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