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Apnea of Prematurity and transcriptional cerebellar changes

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This repository contains the data and R code for the "Apnea of Prematurity induces short and long-term development-related transcriptional changes in the murine cerebellum" paper

❔ Requirements:

  • R version 4.3 or newer
  • R Studio version 2022.07 or newer

💻 Repository structure:

  • DE-AoP-23.RProj: R Studio project (open this first).
  • analysis: R Markdown files for the data analysis, split by data type (PCR & IHC).
    • The first code chunk of any of the .Rmd files will install and load all the packages required for the project, based on the renv.lock file.
  • data: The PCR and IHC data, both raw and processed (when applicable).
  • src: R scripts declaring the functions called within the analysis files (e.g. viz.R for the figures, data.R for the data loading).
  • _configs.yml: Lists the paths to various external files used within the code (e.g. data).
  • _dependencies.yml: Lists the packages required for this project (which will be auto-installed based on the existing renv.lock file).

📜 Licence:

CC-BY

💬 Citation:

  • Paper: Rodriguez-Duboc, A., Basille-Dugay, M., Debonne, A., Rivière, M.-A., Vaudry, D., & Burel, D. (2023). Apnea of prematurity induces short and long-term development-related transcriptional changes in the murine cerebellum. Current Research in Neurobiology, 5, 100113. https://doi.org/10.1016/j.crneur.2023.100113

  • Code: Marc-Aurèle Rivière, & Agalic Rodriguez-Duboc. (2023). ma-riviere/DE-AoP-23: public release (v1.0). Zenodo. https://doi.org/10.5281/zenodo.8139284

✨ Contributors:

  • Marc-Aurèle Rivière:
    ORCID Research Gate

  • Agalic Rodriguez-Duboc:
    ORCID Research Gate

📫 Contact:

For any questions, please contact the primary author of the paper, Agalic Rodriguez-Duboc:
Gmail

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Data & R code for the paper: "Apnea of Prematurity induces short and long-term development-related transcriptional changes in the murine cerebellum"

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