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Merge branch 'master' of https://github.com/marbl/Mash
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Brian Ondov committed Aug 2, 2016
2 parents 0c781eb + f76df1b commit 90754da
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14 changes: 11 additions & 3 deletions doc/sphinx/tutorials.rst
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Expand Up @@ -59,14 +59,22 @@ reference (which there are two of in the sketch file):
Querying read sets against an existing RefSeq sketch
----------------------------------------------------

Download and gunzip the pre-sketched RefSeq archive:
Download and gunzip the pre-sketched RefSeq archive (reads not provided here;
10x-100x coverage of a single genome with any sequencing technology should
work):

.. download::

`RefSeqSketches.msh.gz <http://gembox.cbcb.umd.edu/mash/RefSeqSketches.msh.gz>`_

Sketch the reads (not provided here; 10x-100x coverage of a single bacterial genome
with any sequencing technology should work), using :code:`-m 2` to improve results
Concatenate paired ends (this could also be piped to :code:`mash` to save space by
specifying :code:`-` for standard input, zipped or unzipped):

.. code::
cat reads_1.fastq read_2.fastq > reads.fastq
Sketch the reads, using :code:`-m 2` to improve results
by ignoring single-copy k-mers, which are more likely to be erroneous:

.. code::
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