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Comparing SBSCL simulator

Comparison of SBSCL (https://github.com/draeger-lab/SBSCL) against other simulators for correctness and performance. Comparisons are performed for FBA simulations and ODE simulations.

FBA

The BiGG model collections are compared against results from cobrapy (https://github.com/opencobra/cobrapy) and cameo (https://cameo.bio/index.html).

The bigg database is available from

https://github.com/SBRG/bigg_models

A dump of all models is available from

https://www.dropbox.com/sh/ye05djxrpxy37da/AAD6GrSRTt4MRfuIpprlnLYba?dl=0

The models for comparison are included in this repository in

models/bigg-v1.6

The results of the FBA simulations are available in

results/fba

Objective values are compared between different simulators. Model loading and optimization are benchmarked via repeated execution.

ODE

ODE models are compared between different simulators:

  • roadrunner
  • copasi
  • AMICI

Installation

pip install -r requirements.txt

© 2017-2021 Matthias König

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Comparing SBSCL simulation results with other simulators

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