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calculating patient diversity from VDJ CDR3 sequences recovered from patient BAM files

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mcfefa/OncoDiversity.jl

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OncoDiversity

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Calculating the generalized diversity index for individual patients across a variety of different cancer datasets, including:

  • clustered single cell data
  • individual CDR3 sequences recovered from bulk sequencing files (BAM files)
  • SomaScan analyte intensities from blood samples

Installation

Pkg.develop(PackageSpec(url="https://github.com/mcfefa/OncoDiversity.jl"))

using OncoDiversity

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calculating patient diversity from VDJ CDR3 sequences recovered from patient BAM files

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