FH-PRS

Simple standalone class to calculate FH polygenic risk score accoding to Talmund et al. 2013. Code adopted from Bristol and modernised for python3 and pyVCF. Uses build 38 genomic coordinates.

Usage

python3 fh.py file.vcf

Docker image build

make build

To build the docker image from scratch, using no cached layers:

make cleanbuild

Docker image upload

To upload the built docker image to DockerHub:

make push

Test

This runs against the two files with all or partially missing positions

make test