Skip to content

Commit

Permalink
change wording for poly(A) support
Browse files Browse the repository at this point in the history
  • Loading branch information
tijyojwad committed Nov 13, 2023
1 parent 8bb045d commit 1388ca3
Showing 1 changed file with 2 additions and 2 deletions.
4 changes: 2 additions & 2 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -10,7 +10,7 @@ Dorado is a high-performance, easy-to-use, open source basecaller for Oxford Nan
* [Duplex basecalling](#duplex) (watch the following video for an introduction to [Duplex](https://youtu.be/8DVMG7FEBys)).
* Simplex [barcode classification](#barcode-classification).
* Support for aligned read output in SAM/BAM.
* Experimental support for [poly(A) tail estimation](#polya-tail-estimation).
* Initial support for [poly(A) tail estimation](#polya-tail-estimation).
* [POD5](https://github.com/nanoporetech/pod5-file-format) support for highest basecalling performance.
* Based on libtorch, the C++ API for pytorch.
* Multiple custom optimisations in CUDA and Metal for maximising inference performance.
Expand Down Expand Up @@ -206,7 +206,7 @@ unclassified.bam

### Poly(A) tail estimation

Dorado has experimental support for estimating poly(A) tail lengths for DNA and RNA. Note that Oxford Nanopore cDNA reads sequence in two different orientations and transcript poly(A) length estimation handles both (A and T homopolymers). This feature can be enabled by passing `--estimate-poly-a` to the `basecaller` command. It is disabled by default. The estimated tail length is stored in the `pt:i` tag of the output record. Reads for which the tail length could not be estimated will not have the `pt:i` tag.
Dorado has initial support for estimating poly(A) tail lengths for DNA and RNA. Note that Oxford Nanopore cDNA reads sequence in two different orientations and transcript poly(A) length estimation handles both (A and T homopolymers). This feature can be enabled by passing `--estimate-poly-a` to the `basecaller` command. It is disabled by default. The estimated tail length is stored in the `pt:i` tag of the output record. Reads for which the tail length could not be estimated will not have the `pt:i` tag.

## Available basecalling models

Expand Down

0 comments on commit 1388ca3

Please sign in to comment.