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Gene set analysis #21

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pinin4fjords opened this issue Nov 29, 2022 · 6 comments · Fixed by #33
Closed

Gene set analysis #21

pinin4fjords opened this issue Nov 29, 2022 · 6 comments · Fixed by #33
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enhancement New feature or request
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@pinin4fjords
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pinin4fjords commented Nov 29, 2022

Description of feature

Probably a basic part of any differential analysis (particularly in expression) is a gene set analysis. I propose we have a module for the Broad's GSEA if it's feasible.

Module-level issue nf-core/modules#2584.

@pinin4fjords pinin4fjords added the enhancement New feature or request label Nov 29, 2022
@pinin4fjords pinin4fjords added this to the V0.1 milestone Nov 29, 2022
@pinin4fjords
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Adding GSEA to Bioconda at bioconda/bioconda-recipes#38167 (was a bit a surprised it wasn't there already, but there you go).

@apeltzer
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One could also think about:

  • GSVA
  • PLAGE
  • SingScore

@pinin4fjords
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One could also think about:

  • GSVA
  • PLAGE
  • SingScore

@apeltzer Absolutely - could I persuade you to create issues for each? GSEA will suffice for the MVP I think, and will establish the interface we can hopefully repurpose for the others.

@apeltzer
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apeltzer commented Dec 1, 2022

See #24 , #25, #26

@pinin4fjords
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GSEA module now merged from nf-core/modules#2617

Two additional adapter modules added to generate the correct matrix and class file formats.

@pinin4fjords
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TODO: integration work for this workflow

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