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This CompuCell3D model reproduces chemotaxis by polarization reorientation. With its internal field F-actin, the compartmentalized cell can spontaneously polarize and migrate in random persistent fashion. When sensing an external constant chemical gradient, the cell reorients its polarization, favoring migration in the gradient direction.

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pdalcastel/Single_Cell_Chemotaxis_2.3

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Single_Cell_Chemotaxis_2.3

This CompuCell3D model reproduces chemotaxis by polarization reorientation. With its internal field F-actin, the compartmentalized cell can spontaneously polarize and migrate in random persistent fashion. When sensing an external constant chemical gradient, the cell reorients its polarization, favoring migration in the gradient direction.

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This CompuCell3D model reproduces chemotaxis by polarization reorientation. With its internal field F-actin, the compartmentalized cell can spontaneously polarize and migrate in random persistent fashion. When sensing an external constant chemical gradient, the cell reorients its polarization, favoring migration in the gradient direction.

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