MB Air - 10.7.4 2GB 1.6 GHz i5
Speakers emit scratchy clicks and pops after installation. Quitting the program solves the problem.
Yes, I've encountered this rarely as well, and it was much much worse with earlier versions. I believe it's related to latency calculations.
...OR it could be a sample rate / sample size mismatch. Behavior with sample rates other than 44.1 is still not super-predictable.
Wait— @granteagon, is this on every startup or once after installation only?
Looks like it's only after initial installation.