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How to deal with non-ACGTN IUPAC characters #5

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hoelzer opened this issue Nov 22, 2022 · 0 comments
Open

How to deal with non-ACGTN IUPAC characters #5

hoelzer opened this issue Nov 22, 2022 · 0 comments
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@hoelzer
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hoelzer commented Nov 22, 2022

Right now, all non-ACGTN characters are converted into Ns.

This was by design, to not run into any downstream issues w/ IUPAC characters:
https://github.com/rki-mf1/president/blob/main/president/sequence.py#L23

However, we remove information by the current procedure.

I open this issue for future discussion on the topic.
@hoelzer hoelzer added the question Further information is requested label Nov 22, 2022
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