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bcftools merge: error "[E::bcf_calc_ac] Incorrect allele ("1")" #648

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slzarate opened this issue Jul 12, 2017 · 2 comments
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bcftools merge: error "[E::bcf_calc_ac] Incorrect allele ("1")" #648

slzarate opened this issue Jul 12, 2017 · 2 comments

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@slzarate
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Hello,

I am running bcftools merge using bcftools version 1.5. Here is my output:

bcftools 1.5
...
[W::bcf_hdr_check_sanity] PL should be declared as Number=G
[W::bcf_hdr_check_sanity] PL should be declared as Number=G
[E::bcf_calc_ac] Incorrect allele ("1") in ... at 1:10388

I see that there was a similar issue reported prior to the 1.5 update (#599 and #602), but my version is 1.5 and it's still happening. Any thoughts?

@pd3
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pd3 commented Jul 13, 2017

The two issues are most likely unrelated to your problem. What is the history of the VCF? The warnings and the error message seems quite clear - the VCF has incorrect field, also the PL definition is not what it should be.

@slzarate
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Thanks, I ended up using bcftools concat instead.

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