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Given any coordinates of interest the utility produces a circos interactome coming from HiC-Pro results

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MASTER code for "A CHROMOSOMAL CONNECTOME FOR PSYCHIATRIC AND METABOLIC RISK VARIANTS IN ADULT DOPAMINERGIC NEURONS " Espeso-Gil et al.2020

risk_loci_interactome

Given any GWAS risk loci (or other purpose loci, LOI=loci of interest) and genomic regions of interest (some chromosomes, segments, chrom3Dbeads, COI=cluster of interest) the utility produces a circos interactome coming from HiC-Pro results and reports also a transcription factor binding ranked list of the LOI+LOIconnectome.

Required dependencies

  • bedtools > 2.24.0
  • circos
  • homer > 4.10

Updates (January 2020)

A new version of the code will be available for run it in a automated way directly from HiC-Pro results.

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Given any coordinates of interest the utility produces a circos interactome coming from HiC-Pro results

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