Code for the V1 plasticity disruption experiment (prospective experiment 2) in the Cleo publication. Original model from Wilmes and Clopath 2019. Adapted here by Nathan Cruzado to add closed-loop optogenetic control with Cleo.
Research was conducted in the SIPLab, led by Chris Rozell and Sankar Alagapan at Georgia Tech.
Install the conda environment:
mamba env create -f environment.yml
mamba activate wcm(wcm refers to Wilmes-Clopath Model)
To replicate results in the paper, do all the following (all from repository root as the working directory):
- Run the simulation for all target firing rates and no stimulation:
python run_cleo_sweep.py
- Generate composite figures
python plot_parameter_sweep.py
This code has not been thoroughly tested, so please report any issues you encounter.