MRG: write manysketch
--singleton
sketches incrementally to reduce memory usage
#375
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I'm running into memory issues with
manysketch
--singleton
, likely brought on by the fact that we're storing all the singleton sigs in a list until the end of the file, rather than streaming + sending them to be written. This PR fixes that by sending singletons for writing right after signature generation (before going on to the next read/contig). We then avoid writing singletons at the end of the loop, where they would just be empty template sigs.