Can we run differential kinetics test after stochastic or dynamical mode?

[denvercal1234GitHub]

Hi there,

In the Differential Kinetics tutorial (https://scvelo.readthedocs.io/en/stable/DifferentialKinetics/), scv.tl.differential_kinetic_test was ran right after the scv.tl.velocity with default arguments (i.e., doing the mode = 'stochastic' and not dynamical).

Does that mean I can not perform the differential kinetic test (scv.tl.differential_kinetic_test) if I ran scv.tl.velocity(adata, mode='dynamical')?

But if this is the case, why does the tutorial for Differential Kinetics seemed to suggest that differential kinetics test should be ran after doing dynamical?

Thank you for your help!

"The dynamical model allows us to address this issue with a likelihood ratio test for differential kinetics to detect clusters/lineages that display kinetic behavior that cannot be sufficiently explained by a single model for the overall dynamics. Each cell type is tested whether an independent fit yields a significantly improved likelihood."