FDA CiPA의 의미와 분석 방법에 대한 상세 문서를 작성 중입니다. 요약되어 정리된 정보는 "의약품 심장독성 스크리닝 기술 동향 정보집: 식약처 임상연구과"(2020)에서 확인할 수 있습니다. https://www.nifds.go.kr/brd/m_18/view.do?seq=12505
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Updated
Jun 25, 2020 - TeX
FDA CiPA의 의미와 분석 방법에 대한 상세 문서를 작성 중입니다. 요약되어 정리된 정보는 "의약품 심장독성 스크리닝 기술 동향 정보집: 식약처 임상연구과"(2020)에서 확인할 수 있습니다. https://www.nifds.go.kr/brd/m_18/view.do?seq=12505
Collection of experimental protocols in common patch clamp formats for rapid characterisation of ion channels
Code for analyzing whole-cell patch-clamp data and fitting a Markov model with an evolutionary algorithm, as well as generating figures used in manuscript.
Code to add a mathematical model of voltage-clamp artefacts to your ion channel simulations
Advances in the models for studying cardiovascular physiology: Using parameter sensitivity analysis (PSA) to reduce the length of the voltage protocol
Code to explore gating variables and simulate an action potential using the equations from the 1952 Hodgkin-Huxley paper, "A quantitative description of membrane current and its application to conduction and excitation in nerve"
A nicotinic acetylcholine receptor kinetic model (Edelstein et al. 1996)
T-type Calcium currents (McRory et al 2001)
Availability of low-threshold Ca2+ current in retinal ganglion cells (Lee SC et al. 2003)
Ca-dependent K Channel: kinetics from rat muscle (Moczydlowski, Latorre 1983) XPP
CN Octopus Cell: Ih current (Bal, Oertel 2000)
Retinal Photoreceptor: I Potassium (Beech, Barnes 1989)
Permeation and inactivation of CaV1.2 Ca2+ channels (Babich et al. 2007)
NMDA receptor saturation (Chen et al 2001)
Ca-dependent K Channel: kinetics from rat muscle (Moczydlowski, Latorre 1983) NEURON
Retinal Ganglion Cell: I-A (Benison et al 2001)
Retinal Ganglion Cell: I-Na,t (Benison et al 2001)
Retinal Ganglion Cell: I-K (Skaliora et al 1995)
CA1 interneuron: K currents (Lien et al 2002)
Rat alpha7 nAChR desensitization is modulated by W55 (Gay et al. 2008)
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