It's what the repo description says.
Manual
wget https://github.com/LBPHacker/R216/raw/master/r2asm.lua
./compile.sh
cd peripherals && ./compile.sh && cd..
lua r2asm.lua headless_model=R216DVM headless_out=a.bin <assembly>
./r2vm a.bin ports
- RECV, WAIT and proper R2TERM