Ability to Add Tags to Interpretations

[wrightmw]

Discussed on GCWG call today (10/14/2020). Need to specify what tags would be useful for use in the GCI. A parallel project is currently underway in the VCI (#2093 ).

What are the different use cases in the GCI? Good topic for a Monday call?

@ErinRiggs @courtneythaxton @marinadistefano

[wrightmw]

Tag use cases:

Alerts (e.g. new publication, new ClinVar entry, time for re-evaluation, etc) Auto-tags added by VCI
New ClinVar entry
Triggered by: new ClinVar entry for the variant that is a different (3-level: B/VUS/P) pathogenicity than the approved and submitted to ClinVar curation by the VCEP.
Re-evaluation:
Triggered by: 2 years from approval date for Likely Path/VUS interpretations. (Steven to check details)
Bulk-tagging (e.g. VP added, ClinVar reports)
Added in bulk by system - triggered by curator action
Need two layers: 1: Action and 2: Additional info like ClinVar data, date submitted etc.
Need to be able to sort on both layers.
High priority but dependent on these features,
Free text options (use case: workflow items)
ex: denote all variants that use data from a single paper, reviewed pending approval, awaiting patient data from lab.
Pre-populated set of options: Pilot Variant, Conflict Resolution, Re-curation
See for scoping: https://broadinstitute.atlassian.net/browse/CSP-102
See for mockups: https://docs.google.com/presentation/d/1bhhzm8ZlkwNHGc2WI-UlcZC5m-TwDQMa5NSteG3sKwQ/edit#slide=id.g9ffe19a625_0_11

[wrightmw]

Replaced by ClinGen/gene-and-variant-curation-tools#15