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@wlason you just need to add an if statement in the preprocess prot script, that when intersect rna,prot is not set, to take the intersect of BG and unfilt mdata obs and then run dsb. Been meaning to add the PR for it as we know the fix but just keep forgetting
dsb does not run when half the samples are rna + adt, half the samples are rna only (and no intersection between rna,adt is taken).
fix is to take the intersection of the background: mu.pp.intersect_obs(mdata_bg) prior to mu.prot.pp.dsb
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