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Ozonated Oil

LS edited this page Jan 15, 2021 · 13 revisions
  • This article is incomplete.
Ozonated Oil is an anti-inflammatory and powerful anti-infectant.

It's effective against "bacteria, viruses, fungi, yeast and protozoa." (Study.)

Apply thin layer. Use for 1 week. 1-2x per day.

Research has found ozonated Sesame oil significantly increased the wound closure rate, but ozonated Olive and Linseed oil did not.^ (And the oil must have a peroxide value of 1500.)

Many customers have left positive reviews for this ozonated coconut oil helping their various conditions.

Dr. Shallenberger...
BXO study...


Table of Contents

Patient cases

1. Yeast infections:
Reported success using ozonated oil for yeast infections, which could play a role in some patients' LS (both female and male).

I am highly susceptible to yeast infections, especially when I have to take antibiotics. I am allergic to fluconazole, the medication prescribed for yeast infections... I heat the oil until it is a liquid and pour it into suppository molds to store in the freezer. I use one in the morning and one at night and it completely heals the yeast infection. (Amazon customer review

2. Healing scars:
Reported success using ozonated oil for healing scars, which could maybe benefit LS patients for whom runaway inflammation has made elastic vaginal or foreskin tissue take on characteristics of scar tissue.

My scars are from cystic acne and are dark and deep. They have lightened considerably in just a few weeks... Everything I've put this on slowly gets better and better. (Amazon customer review

Oil type

One study found ozonated Sesame oil significantly increased wound closure, but ozonated Olive Oil and ozonated Linseed oil did not. It confirmed previous findings that only ozonated oil with a peroxide value of 1500 was effective. (If the peroxide value is too high, it delays wound closure.)

This work is the continuance of our previous study where we have shown that only a specific level of peroxidation (expressed as peroxide value about 1500) of ozonated sesame oil is able to significantly accelerate the first phase of wound healing in SKH1 mice (Valacchi et al., 2011). Therefore this study was performed to evaluate the wound healing properties of different ozonated oils... with the same peroxide values...

Only the treatment with Ozonated Sesame Oil had a significant effect on the wound closure rate... It is possible that, in our experimental procedure, the treatment with Ozonated Olive Oil is not able to activate all the pathways involved in the wound healing process... This discrepancy could be a consequence of the low level n-6 present in olive oil, and therefore the lower level of the “bioactive products” such as 4-HNE...

These results demonstrate that application of ozonated oils, especially the ozonated sesame oil with a peroxidation value around 1500, can improve acute cutaneous wound repair in the SKH1 murine (mouse) model by affecting the early phases of the process.

(Ozonated oils as functional dermatological matrices: effects on the wound healing process using SKH1 mice, 2013.)

The study also found that if the oil was too ozonated, it impeded wound healing.

Highly ozonated Sesame Oil (peroxidation levels of 3000) "had an inhibitory effect on the wound healing process. Such an effect could be a consequence of NFkB inhibition (Valacchi et al., 2011). This hypothesis would parallel previous work where exposure of aged mice to ozone would delay wound healing process because the high oxidative levels derived from both ozone exposure and the increased physiological oxidative stress present in the old animals (Lim et al., 2006).

Reduces oxidative stress

One study examining biochemical markers found treating wounds with ozonated air and ozonated sunflower oil decreased oxidative stress.

(Therapeutic efficacy of ozone in patients with diabetic foot, 2005.)

Enhanced microcirculation:

This study states ozone enhances microcirculation.

As for the oral infections (aphthae, HV-I, opportunistic superinfections, or acne) the earliest as possible application of ozonated ointments, by minimizing pathogen diffusion and enhancing microcirculation, reduces the swelling, destroys the pathogen, and allows a rapid healing. (Study.)
That study also confirms ozone use on mucosa (mucosal membranes). Mucosa are the more sensitive skin found in the mouth, the vagina, and, in uncircumcised males, the glans and the inside of the foreskin.

Potential negatives

This older study (2010) found Ozone therapy created negative effects in aged mice. (This study is also discussed above in the oil type study.)

O3 exposure has different effects depending on the age of the mice. In fact, it significantly delayed wound closure in old mice, while in young mice, it led to accelerated trend during the first few days of the exposure...

In a recent study, we demonstrated the detrimental effects of O3 on cutaneous wound healing in the aged animals. In fact, when hairless young (8-week-old) and aged mice (18-months-old) with after full thickness excisional wounds were exposed to 0.5 μg/mL O3 for 6 hours per day the rate of wound closure was significantly delayed in the old group...

One potential explanation for the differential effect in the older animals is that the level of oxidative stress generated by O3 exposure combined with aging causes levels of oxidative stress that inhibits IkBα phosphorylation, thereby resulting in a decline in NFkB activation. This finding is consistent with what mentioned previously that O3 exposure induced skin antioxidants depletion. (Study.)

External links

  1. Latest PubMed studies on ozonated oil.