Modeling of published clinical Ethinylestradiol-Caffeine-DDI studies for model evaluation.
The repository contains a PK-Sim snapshot (*.json) file containing the respective simulations.
The latest release of the snapshot can be found here.
The reference model repositories can be found here:
- Ethinylestradiol OSP PBPK model
- Caffeine model from PK-Sim template database has been used
For your questions and comments about the models please create a new issue. A full publication about models presented is available at: https://www.mdpi.com/1999-4923/12/12/1191 .
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The model code is distributed under the GPLv2 License.